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Crystals of proteins can be used in Crystallography to generate atomic resolutio

Crystals of proteins can be used in Crystallography to generate atomic resolutio

Crystals of proteins can be used in Crystallography to generate atomic resolution structures.
How near to atomic resolution these structures can get is dependent on the quality of the crystal
created, and as a result, on the diffraction pattern produced from that crystal. Around 1
Angstrom would be considered a really excellent protein atomic resolution structure, but
typically this would be around 2.5 Angstroms. Ultimately it is the electron density map that is
generated from the maths used to solve a protein crystal structure that can tell us something of
the atomic structure.
For this workshop identify what the terms:
1) A Diffraction Pattern
2) An Electron Density Map
3) The meaning of Resolution in Crystallography.
(Use YOUR NOTES to produce YOUR answers not Wikipedia, Internet, etc, and make
them YOUR OWN ANSWERS 🙂 )
You can find the resolution of protein crystal structures in many ways from many different data
bases, or the structure itself. Three of the websites given above will show you this information.
4) For this workshop you need to find the resolution of the THREE STRUCTURES ( 4a) to
4c) in answers ). You must use a DIFFERENT WEBSITE in each case; you cannot simply
use one or two of the websites.
5) Show in the material you hand in a picture CLEARLY showing the resolution
information given in the website and identify the websites you got this information in all
THREE cases ( 5a) to 5f) in answers ). Use Print Screen and then crop the image to provide

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