Question: L T-Mobile Wi-Fi 3:09 PM 83% Done 2 of 2 A recent article in JAMA by Mandelblatt et al (2002) com…

02 May Question: L T-Mobile Wi-Fi 3:09 PM 83% Done 2 of 2 A recent article in JAMA by Mandelblatt et al (2002) com…

Posted at 07:46h in 2Past Paper by Exams

l T-Mobile Wi-Fi 3:09 PM 83% Done 2 of 2 A recent article in JAMA by Mandelblatt et al (2002) commpared the societal costs and beneits of human papillomavirus (HPV) testing, Pap testing, and their combination to screen for cervical cancer. The paper studied 18 different population screening strategies-Pap testing alone, HPV testing alone, and Pap plus HPV testing- every 2 or 3 years for women beginning at age 20 and continuing to 65 years, 75 years, and death. The following table summarizes some of the results low cost to high cost). Costs include screening and treatment costs, discounted over the indlividuals expected ifetime Cost (s) QALYs Iner L. Fap every 3 years 6825 27.02 1,825 to age 75 2. HPV every 3 years 6.950 2702 12 3. Pap every 2 years 7,275 2704 4. Pap + HPV every 3 7,400 20125 S. HPV every 2 years 7,450 2704 6 Pap+ HPV every 2 7,925 27.054s to age 75 to age 75 vears to age 75 22,500 450 to age 75 65,000 a. Identify all dominated screening strategies. Explain why each is dominated. b. Calculate the incremental cost, incremental QALYs, and incremental CE ratios for all economically rational strategies (Incremental CE incremental cost/incremental QALYs). Why are these considered economically rational? c. The local health district has asked your opinion on the “best” strategy from a public health perspective. What do you tell them?

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