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Mismatch repair requires ___ enzymatic activity

Mismatch repair requires ___ enzymatic activity

Question
Question 1
Mismatch repair requires ___ enzymatic activity.
Endonuclease
DNA Polymerase
Ligase
All of the above
0.5 points

Question 2
Pyrimidine dimers that are detected by the cell are most likely to be repaired using:
Mismatch repair
Proofreading
Excision repair
0.5 points

Question 3
Conversion of C to G in DNA is an example of a:
Tautomerization
Transversion
Transition
Pyrimidine dimer
0.5 points

Question 4
Shown below is a diagram of a eukaryotic replication bubble with only the template shown. Where on the diagram is the leading strand? (Examine the template DNA very carefully before answering this question!)

A
B
C
D
0.5 points

Question 5
Shown below is a diagram of a eukaryotic replication bubble with only the template shown. Where is the lagging strand? (Examine the template DNA very carefully before answering this question!)
A
B
C
D
0.5 points

Question 6
Shown below is a diagram of a eukaryotic replication bubble with only the template shown. Where is the lagging strand? (Examine the template DNA very carefully before answering this question!)
A
B
C
D
0.5 points

Question 7
What problem is caused by the formation of Okazaki fragments and what is the cell’s solution?
They result in excessive twisting of the DNA, which is relieved by Topoisomerase.
They are short, discontinuous stretches of DNA, which must be annealed using Ligase.
They require DNA synthesis to occur in the 3′ to 5′ direction, which is catalyzed by Primase.
0.5 points

Question 8
What kind of enzyme catalyzes polymerization of DNA?
Endonuclease
Polymerase
Primase
Helicase
0.5 points

Question 9
What problem associated with DNA replication is solved by the formation of Okazaki fragments?
DNA replication begins at multiple origins of replication in eukaryotes.
The two strands of DNA are held together by millions of hydrogen bonds, making separation extremely difficult.
DNA must polymerize in the 5′ to 3′ direction on a template.
DNA polymerization requires an existing chain onto which to add new dNTPs.
0.5 points

Question 10
What would you observe in a cell in which DNA helicase was inactivated?
DNA replication would fail due to the inability to separate the two strands of DNA.
DNA replication would fail due to the absence of a primer for DNA polymerization.
DNA replication would begin, but would eventually stall due to the increase in twisting beyond the replication fork.
DNA replication would occur on the leading strand, but not the lagging strand.

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