10 Jun In the Jak-Stat pathway, the phosphorylation of residues is important
Question
68. In the Jak-Stat pathway, the phosphorylation of residues is important for changing the activity of protein targets in the signalling pathway.
A. Tyr
B. Ala
C. Arg
D. Gly
E. Pho
69. Nuclear receptors and Fos-Jun transcription regulators are similar in that:
A They both “hang-out” in the nucleus.
B They act as dimers.
C. Both have Zinc-binding fingers.
D. They both act to relieve transcriptional repression.
E. They both bind tightly to their respective small molecule ligands.
70. A general name for a protein enzyme that phophorylates another is:
A. kinase.
B. proteinase
C. Iyase
D. tuesdase
E. wednesdase
71. Which of the following property concerning nuclear receptors accounts for their importance in physiology?
A. They control the expression of many target genes throughout the body in a manner coordinated by circulating hormone.
B. They protect DNA from gamma irradiation from nuclear material.
C. They bind to a wide variety of protein ligands.
D. They block regulation of cancer causing genes.
E. They prevent promoters from being tied up in histones.
72. Promoters are essential for evaluating the status of the extracellular environment because they:
A. Integrate information about the local concentration of peptide hormones and small nuclear receptor ligands.
B. Generate probes that are ejected from the cell to determine extracellular status.
C. Facilitate the regulation of genes determining cell proliferation rates.
D. Bind RNA polymerase Il
E. Can facilitate nucleosome formation
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