11 Jun BIOL 125 CASE STUDY – Brian Wilson is an 18-year-old
Question
CASE STUDY!
Brian Wilson is an 18-year-old male student who was healthy until two days ago when he experienced severe abdominal pain, fever, and vomiting. A visit to his GP revealed that he had acute appendicitis. Brian is in excellent health but during the surgery, his body temperature began to rise quite quickly. Medical staff managed this emergency and later diagnosed a genetic condition called Malignant Hyperthermia (MH) that causes a rapid rise in core body temperature, severe muscle contractions and respiratory distress under general anaesthesia (with Halothane).
During Brian’s sedation, Halothane anesthetic caused an adverse effect by binding with Brian’s variant RyR1 ryanodine receptor located in his skeletal muscle cells. At what location in Q2 did this occur? Explain what happened at the molecular level that caused the severe muscle contractions. (4 marks)
Discuss the impact of the hypermetabolic state on chemical demands and adjustments to metabolism in Brian’s skeletal muscle cells ?
Explain what “hypermetabolic” means. (1 mark)
How does ATP contribute to maintaining calcium concentration gradients in muscles? (1.5 marks)
Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Ask A Question and we will direct you to our Order Page at WriteDemy. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Fill in all the assignment paper details that are required in the order form with the standard information being the page count, deadline, academic level and type of paper. It is advisable to have this information at hand so that you can quickly fill in the necessary information needed in the form for the essay writer to be immediately assigned to your writing project. Make payment for the custom essay order to enable us to assign a suitable writer to your order. Payments are made through Paypal on a secured billing page. Finally, sit back and relax.
About Writedemy
We are a professional paper writing website. If you have searched a question and bumped into our website just know you are in the right place to get help in your coursework. We offer HIGH QUALITY & PLAGIARISM FREE Papers.
How It Works
To make an Order you only need to click on “Order Now” and we will direct you to our Order Page. Fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Are there Discounts?
All new clients are eligible for 20% off in their first Order. Our payment method is safe and secure.