11 Jun The M and N factors are glycoproteins
Question
The M and N factors are glycoproteins that are found on the surface of red blood cells antigens, The M and N factors do not cause antibody reactions in human blood transfusions. People with type M blood are homozygous for the M allele, and people with type N blood are homozygous for the N allele. Heterozygous individuals have type MN blood. In a study of population of Inuit living in the Northwest Territories, 512 people have blood type M, 256 had blood type MN, AND 32 has blood type N.
A) Calculate the frequency of each allele, M and N, in the population studied.
B) What would be the expected frequency of each genotype in the next generation, assuming that this population is in genetic equilibrium for the trait?
C) In a second study group, the frequencies of the genotypes were 0.306 MM, 0.491 MN, AND 0.203 NN. Could this second study group have, in fact, come from the previously described Inuit population? Explain your answer.
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