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Old Dominion BIOL 293 – The following is a fragment

Old Dominion BIOL 293 – The following is a fragment

Question
The following is a fragment of the glucocorticoid receptor gene and does not contain the start codon. This gene actually has a mutation at the underlined nucleotide; the wildtype ancestral gene was an A at this position in the DNA.

1. Transcribe and
2. translate this gene fragment (note: the start codon is NOT included and any codons past a STOP are considered part of the 3’ untranslated region/3’ UTR).
3. Underline the mutation.
4. Identify what type of mutation this is and what it will likely do to the GR protein and to the organism (in terms of its ability to respond to stress).

5’ AGA ATG ACT CTA CCC TGC ATG TAC GTC CAA TGT AAA CAC ATG CTG TAT GTT 3

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