11 Jun Oregon BI 331 – Where on the post synaptic neuron
Question
paragraph/sentence questions homwork
Limit: No more than 500 words TOTAL.
Background on completeness of answers: Each of the following questions asks you to interpret information
and justify your answers with the anatomy/physiology knowledge you have been developing. In answering the
following questions, be sure to answer what is being asked. Full points will be awarded for answers with high
precision (as is applicable to our course) and justification for answers. When justifying answers, make the
connection between the anatomy and the observed physiology. DO NOT assume other issues unless they are
explicitly stated.
Citations: You must include your sources for this take home portion. I want to know what sources you are
using. You do not need to include in text citations, but a list at the end of each question. You may include your
lecture notes as a source. For published, non-website citations, please include author, year, title & publisher;
url acceptable for websites. Do not give urls for journal articles. If no sources were used, write the word
“none.”
You must answer all questions.
Question 1 (10 pts): 1.
2. 3. 4.
5. The left image a single post synaptic neuron and 4 presynaptic neurons (numbered 1-4). The trace on
the right shows the membrane potential for the post synaptic neuron over a time period.
(2 pts) Where on the post synaptic neuron would this trace be observed? [Indicate on the drawing
above)
(2 pts) For the time between A and B, which presynaptic neuron/neurons would have been firing?
Explain your reasoning including ions crossing the membrane, the term threshold and one other factor
you consider important.
(2 pts) Assuming the neuron/neurons you stated above (in q 2) were still active at the same level, how
could you explain the change in the trace that occurs after B? Again, explain your reasoning including
ions crossing the membrane and the term threshold.
(4 pts) Create a graph that depicts the effect of increasing Ca2+ influx into presynaptic neuron #1 on AP
frequency of the post synaptic neuron shown. For full credit you must label your axes.
(loss of 1 pt for not included) What sources did you use to answer these questions? See above for
citation format (not included in word count). Question 2: paragraph/sentence questions homwork Above are two traces of membrane potential as a function of time for two human nerve cells. One cell is from
an infant, the other is from an adult. At the arrow, gated channels for ion X open (they do not close in the time
shown) – ion X is the same ion for both infants and adults. [The fundamental chemistry of ion X does not
change.]
1. (8 pts) Given what you know about adult nerve cells, explain the observed traces. In your explanation
of these data include:
a. Specific cellular processes
b. Specific cellular structures involved
c. A likely identity for ion X
d. Why this ion would create the different observed effects on the membrane potential in the
infant and adult. –infant’s neuron is undeveloped
2. (2 pts) Given that the fundamental chemistry of ion X does not change over time, nor does an
individual’s genome, how is it that this different response to the same ion can occur in a single person
at different life stages? What cellular processes would be responsible for this?
3. (loss of 1 pt for not included) What sources did you use to answer these questions? See above for
citation format (not included in word count).
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