12 Jun APU BIO 133 – In order to focus on only the expressed
Question
In order to focus on only the expressed portions of DNA, what type of sequencing can be used?
A.whole-exome sequencing
B.shotgun sequencing
C.pairwise-end sequencing
D.whole-genome sequencing
How can scientists tell how closely related two organisms are?
A.the more genes they share, the more similar
B.by looking at common features, like eye color, hair color, and number of arms
C.by the number of chromosomes that look the same
D.by determining their family trees through genealogy
Linkage analysis determines
A. which two chromosomes two different genes are on by using vectors
B.how close two genes are on the same chromosome by recombination
C.whether two species are related by analyzing their genomes
D.the mutations in an individual by crossing with another and looking at the offspring
Before cellular DNA can be subjected to gel electrophoresis, what needs to happen?
A.amplified and acidified
B.released and isolated
C.modified and cleaned
D.degraded and combined
Three fish species are models for understanding different aspects of genes. Read the descriptions and decide what sort of genetics each is used for.
A. Developmental genetics
B. Evolutionary genetics of skeletal structures
C. Genome analysis
1. Takifugu rubripes – A poisonous marine pufferfish; has an unusually small genome compared to other vertebrates but still carries all essential genes. ______________________
2. Danio rerio – The zebrafish common to amateur aquaria. Many color morphs are available, they breed readily, and embryos are transparent. ________ ________
3. Three-spined stickleback – Stickleback species have variable structure of the bony vertebrae and different numbers of spines on the back. ________
A species that is well studied so that we can learn more about the way we work is call a ________.
A.representative life form
B.organismal representative
C.model organism
D.species stand in
________ hotspots can decrease the accuracy of linkage maps.
A.Variable
B.Cytogenetic
C.Recombination
D.Physical
E.Microsatellite
Isolating all of the RNA out of an organism, subjecting it to reverse transcriptase, and then cloning all of the resulting DNA into plasmids is the process of creating
A.genomic libraries
B.cytogenetic maps
C.cDNA libraries
D.expresses sequence tags
An individual may have a mutation that causes them to break down a drug much more quickly than normal people. They were then provided with a higher dose, which was effective in treating the disease. This is an example of ________.
A.pharmacogenomics
B.toxic drug assay
C.medical allele variation
D.metagenomics
A change in the level of an individual protein in a diseased cell is known as a
A.biomarker
B.protein signature
C.false positive
D.metabolome
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