12 Jun FIU BSC 1010 – glygolysis, pyruvate oxidation
Question
For the following questions (4-6), make a diagram summarizing the main steps in cellular respiration (glygolysis, pyruvate oxidation, Krebs cycle, electron transport chain, chemiosmosis, fermentation) indicating the inputs and outputs of each process. This diagram will help you answer the questions.
4. Cyanide poisoning causes a type of hypoxia by inhibiting cytochrome c oxidase, which is the very last protein in the electron transport chain. A) Explain how/why cyanide inhibition of cytochrome c oxidase interferes with cellular respiration. B) Does the cell have any alternative to keep glycolysis going? C) Explain the purpose of oxygen in respiration.
5. Explain what would happen to ATP production in a mitochondrion that has “leaky membranes”, which would allow protons to diffuse through. Explain and compare to ATP production in a normal cell.
6. Fatty acids are known to be more efficient than carbohydrates at storing energy. A) Compare the net number of ATPs produced from a glucose molecule and a 6-carbon fatty acid. B) Explain the main steps in the energy harvesting process for both molecules and how they relate to the differences in ATP produced. C) Apply what you know about fatty acid metabolism to explain why aerobic exercise is recommended over anaerobic exercise for weight loss. D) When we exercise to lose weight, where is that mass going (do we sweat it out, it turns into heat, becomes digestive waste, how do we eliminate it?)?
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