13 Jun When comparing normal meiosis in human males and females
Question
1.1 When comparing normal meiosis in human males and females
a.) each sperm has 46 chromosomes
b.) in most cases each egg and sperm contain single sex chromosomes
c.) each egg produced contains one more autosome than a sperm cell
d.) all sperm contain the same kind and amount of DNA
e.) each egg has 12 autosomes
1.2 All of the following occur during prometaphase of mitosis in animal cells except
a.) the centrioles move toward opposite poles.
b.) the nucleolus can no longer be seen.
c.) the nuclear envelope disappears.
d.) chromosomes replicate.
e.) the spindle is organized.
1.3 When studying an inherited phenomenon, a geneticist discovers a phenotypic ratio of 9:3:3:1 among offspring of a given mating. A possible explanation for this is a two locus-two alleles at each locus system that exhibits
a. epistasis
b. linkage
c. pleiotropy
d. independent assortment
e. dominance
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1.4. In peas, a tall, yellow-seeded plant is crossed with a homozygous short, green-seeded plant and yields 203 tall, green-seeded plants, 199 short, green-seeded plants, 207 tall, yellow-seeded plants, and 192 short, yellow-seeded plants. The most likely genotype of the tall, yellow-seeded parent is
a. TtYy
b. TTYY
c. ttyy
d. ttYY
e. none of the above
1.5. Given an individual who is heterozygous at 5 loci, how many different gametic genotypes are possible?
a. 25
b. 10
c. 15
d. 32
e. 64
2.1 Dideoxy nucleoside triphosphate (ddNTP)
a. can form a sugar phosphate bond with a new nucleoside triphosphate during DNA synthesis
b. has an oxygen at the 3′ carbon
c. cannot bind to a growing DNA chain
d. has an oxygen at the 2′ carbon
e. will terminate DNA synthesis when incorporated into a growing DNA strand
2.2 The whole-genome shotgun sequencing approach depends primarily on
a. rapidly sequencing thousands of small randomly cloned fragments
b. methodical sequencing a few large cloned fragments of DNA
c. sequencing the bacterial chromosome while it is still intact
d. all of the above
e. none of the above
2.3 TAQ polymerase is so special and useful for PCR because
a. It can replicate DNA faster than any other polymerase
b. It can create amino acid strands complimentary to RNA strands
c. It can synthesize new DNA strands, form a DNA template at high (~ 80C) temperatures
d. It can synthesize new DNA strands, without primers
e. It can act as a ligase
2.4 In the context of DNA sequencing, what is a contig?
a. A set of overlapping DNA fragments
b. The number of nucleotides per centiMorgan
c. The amount of DNA sequence that is found in one read
d. A mature mRNA in which introns have been removed
e. Complement and reversed sequences
2.5
Illumina and 454 sequencing are based on
a. sequencing by synthesis
b. chain termination
c. nanopores
d. sequencing on chips
e. sequencing using chemical degradation
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