13 Jun What is known about the Get pathway for membrane protein insertion
Question
Five pages are needed with works cited page.
What is known about the Get pathway for membrane protein insertion?
For Figure 1D, describe the experimental set-up and how the results indicate the Get3 can take Sec22 from Get4/5.
How do we know that Get3 transport to the ER is dependent on Get1/Get2 (Fig. 1E)?
In Figure 2A, which lane indicates that Sgt2 is required for association of Get5 with the rest of the protein complex? Explain your answer.
The experimenters induce a mutation in Sgt2 that reduces binding of Hsps to Sgt2. Does this affect the binding of Sgt2 and Sec22?
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