16 Jun UGA BCMD 3100 -Discussed the challenges of developing effective vaccines
Question
Dr. Tarleton discussed the challenges of developing effective vaccines for parasitic diseases caused by protozoa. Malaria is a devastating human disease in tropical regions of the world that is caused by the protozoans in the genus Plasmodium. Recent advances in the development of a malarial vaccine by Glaxo-Smith Kline and the PATH Malaria vaccine initiative are encouraging for bringing a new tool to reduce the incidence of malaria. The vaccine RTS,S produced by this consortium is the first vaccine that has completed Phase 3 testing.
a) (10 pts) What is the name of the Plasmodium protein that is the target antigen which is the basis for the GSKRTS,S vaccine? Sketch the life-cycle of Plasmodium, or insert a diagram, and indicate what stage (s) the antibodies elicited by the RTS,S vaccine target.
b) (20 pts) What are thought to be the functions of the ‘targeted’ Plasmodium protein in the human host?
c) (20 pts) Describe experiments done to show the safety and efficacy of the GSK-RTS,S vaccine in Phase 3 clinical trials in infants and children in Africa; include a summary of the final results and describe the efficacy of the vaccine.
Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Ask A Question and we will direct you to our Order Page at WriteDemy. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Fill in all the assignment paper details that are required in the order form with the standard information being the page count, deadline, academic level and type of paper. It is advisable to have this information at hand so that you can quickly fill in the necessary information needed in the form for the essay writer to be immediately assigned to your writing project. Make payment for the custom essay order to enable us to assign a suitable writer to your order. Payments are made through Paypal on a secured billing page. Finally, sit back and relax.
About Writedemy
We are a professional paper writing website. If you have searched a question and bumped into our website just know you are in the right place to get help in your coursework. We offer HIGH QUALITY & PLAGIARISM FREE Papers.
How It Works
To make an Order you only need to click on “Order Now” and we will direct you to our Order Page. Fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Are there Discounts?
All new clients are eligible for 20% off in their first Order. Our payment method is safe and secure.