24 Jun On the basis of these signs, wh
On the basis of these signs, which of the following ONE disorders would you suspect AND WHY? RULE OUT the OTHER FOUR disorders by providing detailed anatomical & physiological descriptions based on the clinical diagnostic data provided, along with specific clinical manifestations.
a. Addisons disease
b. Cushings disease
c. Pheochromocytoma
d. Hypoaldosteronism
e. Hyperthyroidism
Diagnostic and laboratory tests are ordered, and an appointment with an endocrinologist is arranged. A few of the pertinent test results are listed below:
Plasma cortisol levels: 40 g/dL (taken at 7:00 am)
Plasma ACTH: 100 pg/mL (taken at 7:00 am)
X-ray of skull: erosion of the sella turcica (sphenoid bone)
MRI of pituitary gland: abnormal mass detected
What is the probable cause of Sandras disorder? WHY?
2. Describe the specific physiological, anatomical and DETAILED genetic LOCI etiology of BOTH sickle cell anemia AND ALL TYPES OF thalassemia (α and β). Also, detail the exact clinical manifestations & potential treatment options for these medical pathologies.
3. A 20-year-old woman lost consciousness while in a shopping mall. She had no identification with her. In the emergency room, the physician assessed her comatose state, noting among other physical findings, rapid respirations, and then ordered blood and urine studies. The physician obtained the following laboratory test results:
Blood Studies:
Complete blood count (CBC): within normal limits
Serum electrolytes:
Sodium: 135 mEq/L
Potassium: 4.1 mEq/L
Chloride: 100 mEq/L
Blood glucose: 800 mg/dL
Blood pH: 7.23
PaCO2: 30 mm Hg
HCO3- : 12 mEq/L
Blood urea nitrogen (BUN): 9 mg/dL
Urinalysis:
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