28 Jun GIVEN YOUR KNOWLEDGE OF ENZYMES ACTIVITY AND INHIBITORS, SPECULATE ABOUT THE MECHANISM BY WHICH ETHANOL PREVENTS ETHYLENE GLYCOL POISONING
Ethylene glycol, the main ingredient in antifreeze, is an odorless, colorless, sweet-tasting water soluble chemical that, when ingested, is a toxic poison. the treatment for ethylene glycol poisoning involves emergency procedures
that include intravenous doses of ethanol for several hours. to understand how this treatment works, you need to know that ethylene glycol is metabolized by the enzyme alcohol dehydrogenase (ADH) into four products, and
these products are the actual toxic agents. If this reaction can be inhibited, then the kidneys will eliminate the ethylene glycol intact before the toxins are produced. chemists know that ADH has 100x greater affinity for ethanol
than for ethylene glycol.
Given your knowledge of enzyme activity and inhibitors, speculate about the mechanism by which ethanol prevents ethylene glycol poisoning.
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