23 Jul WHAT WOULD HAPPEN TO A T CELL IF A MUTATION WERE INTRODUCED IN LCK?
Describe the structure of the B-cell receptor (BCR Show more PLEASE PUT ANSWERS IN OWN WORD FOR 3500 POINTS 7. Describe the structure of the B-cell receptor (BCR). How is the BCR able to trigger a signal transduction pathway when its cytoplasmic tail is only 3 amino acids in length? Outline BCR signal transduction from the point of antigen binding through the NF-B pathway. What is the result of signal transduction events from the BCR? (10 marks) 8. What is agammaglobulinemia? What enzyme is mutated in these patients and what is this enzymes function? What happens to people with this disorder? (5 marks) 9. What is Lck and why is it important? What would happen to a T cell if a mutation were introduced in Lck? (5 marks) Show less
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