23 Jul WHICH OF THE GLYCOLYTIC ENZYMES HAS THE GREATEST AFFINITY FOR THEIR SUBSTRATE AND WHICH THE LOWEST AFFINITY?
Use the following data obtained from studies on the glycolytic pathway to answer the questions bel Show more Use the following data obtained from studies on the glycolytic pathway to answer the questions below: a) Identify which of the glycolytic reactions are more near- and which are more far-equilibrium in nature. Explain why. b) Identify which of the reactions are likely to be very sensitive to small changes in substrate or product concentration. c) Which of the glycolytic reactions has the most negative G and what does this mean in terms of the whole pathway? d) Which of the glycolytic enzymes has the greatest affinity for their substrate and which the lowest affinity? What are the metabolic consequences of such affinity differences? e) List the factors that play a role in determining the flux through the pathway. Show less
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