23 Jul WHY WAS IT NECESSARY TO LABEL THE STREAM BETWEEN THE MIXER AND THE DRYER?
The hormone estroge Show more Elementary Principles of Chemical Processes 4th edition Chapter 4 question 39 The hormone estrogen is produced in the ovaries of women and elsewhere in men and post-menopausel women and is also given in hormone replacement therapy a common treatment for women who have had a hysterectomy. unfortunately it also binds to estrogen receptor in breast tissue and can activate cells to become cancerous. tamifoxen is a drug that aso binds to estrogen receptors but does not activate cells in effect blocking the receptors from access to estrogen and inhibiting the growth of breast cancer cells Tamifoxifen is given in tablet form. in the manu. process fine ground powder contains tamoxifen (tam) abd 2 inactive filers- lactose monohydrate (lac) and corn starch (cs). the powder is mixed with a 2nd stream with water and suspended polyvinylpyrrolidone ((pvp) binders to keep the tablets from crumbling. the slurry leaving the mixer goes to a dryer where 94.2% of the water is vaporized. the wet powder leaves the dryer containing 8.8%wt tam 66.8% lac 21.4%cs 2% pvp and 1%water. after additional processing the powder forms into tablets. 17.13kg of wet powder is required for the production . A) taking a basis of 100000 tablets produced draw and label a process flowchart labeling masses of individual component rather than total masses and component mass fractions.it is unnecessary to label the stream between the mixer and the dryer. carry out a degree of freedom analysis of the overall 2 unit process B) calculate the masses and compositions of the streams that must enter the mixer to make 100000 tablets. C) Why was it necessary to label the stream between the mixer and the dryer? under what circumstances would it have been necessary? D) go back to the flowchart of part A. without using the mass of the wet powder (17.13 kg) or any of the results of part B in your calculations determine the mass fractions of the stream components of the powder fed to the mixer and verify that they match your solution to part B. (Hint: take basis of 100 kg of wet powder) E) suppose a student does part D before doing part B and relabel the powder feed to the mixer on the flowchart of part A with an unknown total mass m1 and the three now known mole fractions. (sketch the resulting flowchart) the student then does a degree of freedom analysis counts 4 unknowns (masses of the powder pvp and water fed into mixer and mass of water evaporated in the dryer) and 6 equations (5 material balances for the 5 species and the percentage evaporation) for a net of -2 degrees of freedom. since there are more equations that unknowns it should not be possible to get a unique solution for the four unknown. nevertheless the student writes 4 equations solves the 4 unknowns and verifies that all of balance equations are satisfied. there must have been a mistake in the degree of freedom calculation what was it? Show less
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