23 Jul EXPLAIN THIS PHENOMENON IN MOLECULAR TERMS.
In normal mitochondria the rate of electron transfer is tightly coupled to the demand for ATP. When Show more In normal mitochondria the rate of electron transfer is tightly coupled to the demand for ATP. When the rate of use of ATP is relatively low the rate of electron transport is low. When demand for ATP increases electron-transport rate increases. Under these conditions of tight coupling the number of ATP molecules produced per gram of oxygen consumed when NADH is the electron donor-the P/O ratio is about 2.5-3.0. Ingestion of uncouplers causes profuse sweating and increase in body temperature. Explain this phenomenon in molecular terms. What happens to the P/O ratio in the presence of uncouplers. Show less
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