23 Jul WHAT IS THE PROBABILITY THAT THE CHILD WILL HAVE THE DISEASE?
Consider the following pedigree of a rare autosomal recessive disease. Assume all people marrying in Show more Consider the following pedigree of a rare autosomal recessive disease. Assume all people marrying into the pedigree do not carry the abnormal allele. (8 points) (a) If individuals A and B have a child What is the probability that the child will have the disease? HINT: It helps to first assign genotypes to all individuals in the pedigree. For individuals where several genotypes are possible use the information in the pedigree to calculate the probability of each possible genotype. (b) If individuals C and D have a child what is the probability that the child will have the disease? (c) If the first child of C * D is normal what is the probability that their second child will have the disease? (d) If the first child of C * D has the disease what is the probability that their second child will have the disease? Show less
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