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WHAT CHROMOSOMAL ALTERATION DESCRIBED HERE?

WHAT CHROMOSOMAL ALTERATION DESCRIBED HERE?

In normal prostate cells ERG is turned off and TMPRSS2 is turned on. when parts of TMPRSS2 in the pr Show more In normal prostate cells ERG is turned off and TMPRSS2 is turned on. when parts of TMPRSS2 in the prostate become fused to ERG. ERG is turned on. Once activated ERG drives cancer development by unapropriatelt turning on or off ther genes. This gene is the most specific marker of prostate cancer yet to be found. Q1. What chromosomal alteration described here?(are more than one answer) Q2. where does this chromosomal alteration occured (in gametes or in somatic cells) Q3. Speculate on how this chromosomal alteration might be involved in this cellular transformation(i.e what effects might this alteration have on the CELL CYCLE?) Show less

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