A 50-year-old male had a total thyroidectomy followed

A 50-year-old male had a total thyroidectomy followed by thyroid hormone-replacement therapy. Thirty-six hours later he developed laryngeal spasms, a mild tetany, and cramps in the muscles of the hands and arms. The following tests were performed:Urine calcium 1.1 mmol/L

Urine phosphorus 0.1 g/day

Plasma calcium 0.39 mmol/L

Plasma phosphorus 0.28 mmol/L Calcium gluconate and vitamin D (calcitriol) were given orally each day and the tetany and laryngeal spasms were alleviated.

Discuss the cues that are evident in the scenario in light of your knowledge of the heirarchy of endocrine control, endocrine organs, feedback loops, hormones and their target tissues to explain the abnormal health state (Demonstrate your understanding of the structure and function of the endocrine system; analyse and integrate data from clinical scenarios to explain the reasons for the abnormal endocrine health state).

If you indicate a single ‘diagnosis’, you should also indicate any other possible diagnoses and why you have rejected them

Discuss the possible intent of any diagnostic test or therapeutic intervention in the management of the patient’s health condition (analyse and integrate data from clinical scenarios to explain reasons for and consequences of common clinical interventions).

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