11 Jun BCH 311 – Fructose can enter glycolysis at two distinct
Question
6.Fructose can enter glycolysis at two distinct points, depending on the tissue. How is fructose metabolized in adipose tissue?
A. Fructose is converted to fructose-1-phosphate
B. Fructose is cleaved to GAP and DHAP
C. Fructose is converted to fructose-6-phosphate
D. Fructose is cleaved to two molecules of GAP
E. Fructose is converted to glucose, which enters the pathway
7.What is the significance of the fact that glucokinase is found in liver and β cells of the pancreas and that hexokinase is found in most other cells?
A. Hexokinase is not inhibited by glucose 6-phosphate, allowing accumulation in muscle for storage as glycogen
B. Glucokinase phosphorylates glucose when blood glucose levels are low
C. The role of hexokinase is to provide glucose 6-phosphate for the synthesis of fatty acids
D. Hexokinase has a high KM, so it does not become saturated until blood glucose levels are extremely high
E. At low glucose levels, very little is taken up by the liver, so glucose is spared for other tissues
10. In gluconeogenesis, the phosphoryl donor for the formation of phosphoenolpyruvate is?
A. PEP
B. ATP
C. Pyruvate
D. GTP
E. Pi
11.The enzyme involved in shuttling carbons in gluconeogenesis from the mitochondria to the cytosol is called?
A. Citrate synthase
B. Malate dehydrogenase
C. Oxaloacetate transferase
D. Pyruvate kinase
E. Oxaloacetate reductase
12.The glucose 6-phosphatase reaction takes place in which cellular location?
A. Plasma membrane
B. Cytoplasm
C. Mitochondria
D. Nucleus
E. Endoplasmic reticulum
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