11 Jun BIOL 115 – The Cell Cycle and Mitosis
Question
The Cell Cycle and Mitosis
• Which type of cells within our bodies use mitosis to reproduce?
• Does mitosis create a cell that is different or the identical to the parent cell
undergoing division?
• Describe the DNA found in sister chromatids.
• Describe the DNA found in homologous chromosomes.
• What occurs during the following stages of the cell cycle?
1) G1 Phase
2) S Phase
3) G2 Phase
4) M Phase
• What are the phases of mitosis? What events occur in each phase? (To
best understand these processes, draw the phases in order and provide a
brief description of cellular events at each stage.) •
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• Does mitosis separate homologous chromosomes, sister chromatids, or
both?
What is cytokinesis?
Which fibers of the cytoskeleton contract to pinch parent and daughter
cells apart from one another in animals?
How do microtubules move chromosomes to the two poles of a dividing
cell?
How are centrioles involved in this process?
How do plants form two complete cells during cytokinesis?
How do bacterial cells reproduce?
The cell cycle is controlled at “checkpoints”. What occurs at each of the
following checkpoints?
G1 Checkpoint
G2 Checkpoint
M Checkpoint
How do cyclin and cdk act to control the G2 checkpoint?
If presented with the schematic of the M checkpoint, you should be able to
explain perturbations to the system as well as if the cell will divide or stall
at metaphase.
Cancerous cells form when the cell cycle checkpoints do not function
correctly and a continues to divide even though it is damaged in some
way. How does the protein p53 function to keep these cells from dividing?
Normal cells follow certain rules of growth that cancerous cells do not
follow. What are these rules (provide a short definition for each as well)?
What is the difference between a benign tumor and a malignant tumor?
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