10 Jun BIOLOGY 232 – What is the typical resting membrane potential
uestion
1.What is the typical resting membrane potential (or voltage) in a neuron?
2. What are the two events that might occur to cause the membrane voltage to change from its
typical resting membrane potential (RMP).
3.How the concentration gradient and electrical charge influence the net movement of ions into and out of the neuron. Then, for each of the three ions, describe
the influence of both electrical and concentration gradient forces on ions’ net movement in or out of the cell.
4.Why a neuron’s voltage returns to about -70 mV following a graded potential that does not cause voltage to reach threshold. That is to say, what changes in ion flow occur before RMP is reached? Why is there no net movement of ions (except via the pump and continuous inflow of sodium) once RMP is reached?
5.Is RMP would increase, decrease, or stay the same if the sodium-potassium ATPases stop working for several hours. What is the rationale for your prediction? How would the persistent failure of the pumps influence the ability of the neuron to generate action potentials? (Assumethat the neuron will not burst because of a possible increase in the concentration of ions in the neuron.
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