27 Jun BIOLOGY Assignment
Question
1. (1 point) Evaluate the following lac operon partial diploids. Indicate whether the production of functional ?-galactosidase from lacZ and of permease from lacY is “inducible”, “constitutive”, “absent” or “noninducible” for each partial diplod
a. F’ I+-p+o+Z+Y+ X F- I+p+o+Z-Y-
b. F’ I+-p+ocZ+Y- X F- I+p+o+Z-Y+ c. F’ I+-p+ocZ-Y+ X F- Isp+o+Z+Y+
2~3 Describe the effects on attenuation and on tryptophan synthesis of the following mutations of the two tryptophan codons (UGGUGG) in the attenuator region of operon.
2. (1 point) The tryptophan codons are mutated to UAGUGG. 3. (1 point) The tryptophan codons are mutated to UUGUUG.
4. (1 point) What would be the phenotype of a null mutation in the CRP protein gene in the regulation of Lac operon and why?
5. (1point) What would be the phenotype of a “constitutively expressed” mutation in the CRP protein gene in the regulation of Lac operon (i.e. CRP proteins are always highly expressed) and why?
6. (2 points) A repressible operon system, like the trp operon, contains three genes, G, Z, and W. Operon genes are synthesized when the end product of the operon synthesis pathway is absent, but there is no synthesis when the end product is present. One of these genes is an operator, one is a regulatory protein, and the other is a structural enzyme involved in synthesis of the end product. In the table below, “+” indicates that the enzyme is synthesized by the operon, and “-“ means that no enzyme synthesis occurs. Use this information to determine which gene corresponds to each operon function.
??Present
G+Z+W+ ? ? +
G-Z+W+ ? ? + G+Z-W+ ? ? – G+Z+W- ? ? ? ? ? + G-Z+W+/G+Z-W- ? ? ? ? ? + G+Z-W+/G-Z+W- ? ? ? ? ? + G-Z-W-/G+Z+W+ ? ? ? ? ? + G+Z+W-/G-Z-W+ ? ? ? ? ? +
7. (1 point) Gene A is maternally imprinted (silenced) while Gene B is paternally imprinted when imprinted silencing occurs. A Mom with Genes A and B imprinted and a Dad with an imprinted Gene A have a daughter and a son. The children then marry individuals known not to be silenced for either gene. What is the imprint status of the daughter and son respectively? If each marriage results in the birth of a daughter and a son, what would you expect the imprint status of genes A and B to be for the grandchildren?
8 ~ 9. On a rare occasion, human can be born with a condition known as “uniparental disomy”. This happens when an individual inherited both copies of a chromosome from one parent but no copies from the other parent. For example, abnormal sperm that lacks chromosome 15 can fertilize an egg that contains two copies of chromosome 15. This is known as maternal uniparental disomy 15. Alternatively, there are cases of paternal disomy 15 (an abnormal sperm with two copies of chromosome 15 fertilizes an egg with no copies).
8. (1 point) If a female is born with paternal disomy 15, would you expect her to be normal or have Angelman syndrome (AS) or have Prader-Willi syndrome (PWS)? And explain why?
9. (1point) Would you expect her to produce normal offspring or offspring affected with AS or PWS?
Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Ask A Question and we will direct you to our Order Page at WriteDemy. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Fill in all the assignment paper details that are required in the order form with the standard information being the page count, deadline, academic level and type of paper. It is advisable to have this information at hand so that you can quickly fill in the necessary information needed in the form for the essay writer to be immediately assigned to your writing project. Make payment for the custom essay order to enable us to assign a suitable writer to your order. Payments are made through Paypal on a secured billing page. Finally, sit back and relax.
About Writedemy
We are a professional paper writing website. If you have searched a question and bumped into our website just know you are in the right place to get help in your coursework. We offer HIGH QUALITY & PLAGIARISM FREE Papers.
How It Works
To make an Order you only need to click on “Order Now” and we will direct you to our Order Page. Fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.
Are there Discounts?
All new clients are eligible for 20% off in their first Order. Our payment method is safe and secure.