15 Jun Bromouracil is an analogue of thymine that normally pairs with adenine
Question
5-Bromouracil is an analogue of thymine that normally pairs with adenine. However, 5-bromouracil frequently pairs with thymine. Explain.
The electron withdrawing effect of the bromine increases the likelihood of uracil enol formation. This enol mimics the hydrogen-bonding pattern of cytosine. Therefore, this base cane paired with guanine.
What are the two primary characteristics that distinguish hematopoietic stem cells and progenitor cells?
Stem cells are capable of self-renewal and can give rise to more than one cell type, whereas progenitor cells have lost the capacity for self-renewal and are committed to a single cell lineage. Commitment of progenitor cells depends on their acquisition of responsiveness to particular growth factor.
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