26 Jun How do changes in endothelial and immune cell function contribute to cancer
Question
Biology of Cancer
Delivery must be by 3PM August 17, 2013– payment will be voided if you cannot deliver by this time
Short Answer: Please be concise with your answers and as specific as possible.
1. Genes involved in cell cycle activity/survival are mutated to contribute to the development of cancer. Name the two categories of genes related to cell division that are mutated and how mutations affect their function and lead to cancer.
2. How do changes in endothelial and immune cell function contribute to cancer?
3. Name two carcinogens and how each contributes to a specific type of cancer. Include information on how they act as carcinogens.
4. Humans are diploid organisms. What does this mean, and how does this help prevent cancer when a gene is mutated? Provide an example in your response.
5. How can active transport activity by cells contribute to cancer?
6. How is it that changes in membrane fluidity can lead to tumor development?
7. What type of standard treatment should be used for metastatic adenocarcinoma? Explain your response.
8. What type of secondary/alternative treatment strategy should be used for treatment against hemangioma? Explain your response.
9. Assume that two individuals (A and B) develop the same type of cancer. Both individuals are given the best treatment found to be effective against cancer. Individual A responds well to treatment, while individual B does not. Using what you have learned, provide a specific type of cancer and an explanation for why there was a difference in response to treatment.
10. Name a type of virus that causes cancer and explain how it works. Include the type of cancer it causes in your response.
11. Genetic instability is the accumulation of DNA mutations, especially in cancer cells. How is genetic instability prevented in healthy cells?
13. Name a type of bacteria that causes cancer and explain how it works. Include the type of cancer it causes in your response.
14. Why does it make sense that the majority of cancers are non-hereditary?
15. What genetic profiling method do you think is best in identifying genes related to cancer? Include an explanation of why this method is better than other methods.
16. Which cancer screening method is best? Explain the type of cancer(s) it detects and why it is better than other methods.
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