23 Jul HOW DOES LINE1 INTEGRATE INTO THE GENOME?
How does Line1 integrate into the genome? Show more How does Line1 integrate into the genome? SINE and ALU are proteolyzed by ORF1p and ORF2p which are then shuttled into the nucleus and promote recombination ORF1p and ORF2p are encoded by Line1 mRNA and help shuttle the mRNA into the nucleus where ORF2p nicks the genome and reverse transcribes L1 ORF1p and ORF2p are encoded by Line1 mRNA and induce monocistronic microsatellite stabilization withing the genome Line1 elements are duplicated during DNA replication because the cause Non homologous end joining during cell division Show less
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