11 Jun Just how much brain swelling are we talking about
Question
Just how much brain swelling are we talking about? The volume of a human brain is normally about 1,200cm3. e concentration of solutes in the cerebrospinal uid (the fluid that surrounds the brain and other parts of the
central nervous system) is normally about 300mM.
Normally, what is the concentration of solutes in your brain cells? Please explain your reasoning.
If the concentration of solutes in the cerebrospinal fluid fell to 280mM due to overconsumption of water and loss of electrolytes through sweating, what would happen?
Estimate how much the brain would swell due to osmosis if the concentration of the cerebrospinal fluid fell to 280mM. In other words, find what the new volume of the brain would be once equilibrium was reestablished. Assume that (i) the cerebrospinal fluid is constantly replenished, so its solute concentration won’t change; (ii) only water is passing across the cell membranes into brain cells (not solutes); and (iii) the volume of the brain is mostly water.
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