11 Jun Labrador Centronuclear Myopathy (CNM) is genetic
Question
Labrador Centronuclear Myopathy (CNM) is genetic disease in Labrador retrievers that results in insufficient muscle function, poor muscles tone, exercise intolerance, and awkward gait. CNM only develops in dogs that are homozygous recessive for the PTPLA gene. You are a dog breeder and there is one puppy in a new litter that has CNM. Neither of the puppy’s parents have CNM.
1) What is the parents’ genotype for the gene responsible for CNM (please use “P” for the dominant allele and “p” for the recessive allele?
2) If you were to breed these two dogs again, what is the probability that a puppy in the next litter will have CNM?
3) If you were to breed the puppy that has CNM, how many of the future offspring will be carriers for CNM 2pts?
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