16 Jun Monoclonal antibody technology and new advances
Question
Monoclonal antibody technology and new advances.
a. Describe conventional monoclonal antibody technology. Use an example in your explanation, but do not rely on Dr. Meagher’s figures or examples. Who were the first to develop monoclonal antibodytechnology?
b. What was the initial technology patented by Dr. Meagher and developed by Abeome to improveproduction of monoclonal antibodies? Explain in detail and explain why it is “better” than conventionaltechniques—what are the problems with making monoclonal antibodies in a conventional way.
c. What is newest innovative technology developed by Dr. Meagher and Abeome to improveproduction of monoclonal antibodies? Explain in detail and explain why it is “better” than conventionaltechniques and the first technology patented by Dr. Meagher.
d. Choose one antibody target being pursued by Abeome and describe how the antibody would be commercially attractive, i.e., what disease or disorder would it target, what is the market size, and what would be the mechanism by which the antibody would affect the disease or disorder?
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