10 Jun Mutations in codons – An experimenter is studying a gene
Question
Mutations in codons
I am working on a genetics assignment and am completely stumped on this problem. I have looked at it for hours and cannot figure it out. The biggest problem I am running into what kind of mutagen could induce these specific changes. I’ve tried various ways of frame shifting, but nothing seems to be working here.
Here is the problem:
An experimenter is studying a gene that codes for the polypeptide phe-his-gly-cys-gly
He treats the cell with different mutagens that cause the following changes to the protein:
Treatment 1: phe-his-gly-cys
Treatment 2: ser-his-gly-cys-gly
For each treatment, describe the exact mutagenic event (e.g. transition, transversion, frameshift, etc), the most likely codonsequence, and the type of mutagen used.
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