26 Jun Nucleic Acid Structure Questions Explain how you know the
Question
Nucleic Acid Structure Questions
1) .0/msohtmlclip1/01/clip_image002.jpg”>Explain how you know the molecule at the right is a nucleic acid.
2) Is this molecule DNA or RNA? How do you know?
3) Why are nucleic acids, ‘acids’? In other words, what makes them acidic?
4) Label the 3’ and 5’ ends of the molecule below.
5) Circle a single nucleotide and label the three components (sugar, phosphate, nitrogenous base)
6) How many nucleotides make up this nucleic acid?
7) Nucleic acids are always constructed 5’ to 3’. In other words, new nucleotides are always added to the 3’ end. Put a star showing where the next nucleotide will be added.
8) Thymine and cytosine are pyrimidine nitrogenous bases with a single ring. Thymine has two carbonyl functional groups on its ring system. Cytosine has a carbonyl and amino function group on its ring. Label these nitrogenous bases T and C, respectively.
9) Adenine and guanine are pure nitrogenous bases with two rings. Adenine has a single amino functional group on its rings while guanine has a carbonyl functional group and amino group. Label these nitrogenous bases A and G, respectively.
10) Examining the molecules and functional groups, explain why just two hydrogen bonds will form between A and T but three form between G and C.
Replication: The following represents the nucleotide sequence in the gene for a short polypeptide (protein). The strand shown is the template strand.
3’
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
5’
T
A
C
C
C
T
T
A
A
C
C
A
A
T
G
A
G
T
A
T
T
1. Replication: Beneath the template strand above, write the nucleotide sequence for the non-template (anti-sense) strand of this segment of DNA. Be sure to include the designation for the 3’ and 5’ ends.
2. During replication of the template strand, the complementary (non-template) strand would be made from the:
a. right to the left b. left to the right
3. If the DNA polymerase/replication fork moves along the template DNA from the LEFT to the RIGHT replicating the DNA, the new complementary strand is made in:
a. one long piece
b. a series of short fragments
c. impossible to determine from the info provided
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