25 Jun One important function of the kidneys is to regulate blood
Question
One important function of the kidneys is to regulate blood pH. During acidosis, the kidneys secrete H+ into the lumen of the nephron by several pathways. Focusing on the two primary active transport pathways (H+-ATPase and the H+- K+-ATPase pump):
a. Describe how they work to return pH to normal (what happens to extracellular fluid levels of Na+ and K+ in the process?).
b. Pick one of the pumps and describe what is known about it structure and function at the molecular level. Use your understanding of H+ transport through proteins to comment on structures that likely exist, even if little data exist to prove it.
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