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PSet 2 – A flock of Dorset sheep at Alice’s Farm

PSet 2 – A flock of Dorset sheep at Alice’s Farm

Question
Problem Set 2
Name: __________________________________________
Due on Wednesday, December 14, during class! NO late acceptance! Please print and
complete on worksheet.
1. A flock of Dorset sheep at Alice’s Farm in Hadley produces fleece with a mean weight of 5.9
lbs. Farmer Alice would like to increase fleece weights and chooses individuals with a mean
weight of 6.4 lbs as breeding stock. The next generation has 15 individuals with the following
fleece weights (lbs): 5.9, 6.0, 6.0, 5.8, 6.2, 6.1, 6.4, 5.9, 5.8, 6.3, 6.2, 6.5, 6.1, 6.0, 6.3.
a) What is the heritability for fleece weights? b) What does this value mean? c) A flock of Dorsets raised in Central Australia is expected to have the same heritability value.
True or False (circle one) and justify your answer. 2. An autosomal recessive disease is found with a prevalence of 1/12,000 in the US population.
You have a younger sibling with this disease and assume that you might be a carrier. Prior to
attempting to conceive you and your partner get tested for the presence of the recessive allele.
a. What is the frequency of the recessive allele in the population? b. What is the frequency of the dominant allele in the population? c. What is the chance that your partner is a carrier for this disease? 1 Problem Set 2
Name: __________________________________________
Due on Wednesday, December 14, during class! NO late acceptance! Please print and
complete on worksheet.
3. A population of caribou in Alaska has decreased dramatically during the past decade. It is
unclear whether this is due to A) environmental changes due to global warming or if it may be
due to B) new roads that have isolated populations forcing increased inbreeding. You have been
asked to assess the genetic health of a population of caribou in Alaska. You genotype 2,000
individuals in this population with a microsatellite marker (that produces the indicated bands on
a gel) and obtain the following results: Type I =1,140 individuals; Type II =140 individuals;
Type III =720 individuals. Show your work.
Type I I Type II Type III 400 bpp 150bp a. Is the population in Hardy-Weinberg equilibrium (show all work)? b. What is your conclusion about the genetic health of the population and the reason for the
decreased population and why? 2

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