11 Jun UH Clear BIOL 5332 – Describe the three classes of carcinogens
Question
1. Describe the three classes of carcinogens and their sub classes; describe the role each plays in the cancer process and give chemical examples.
2. Describe six points in the cancer process where the process can be inhibited by chemicals or other substances; include specific examples and descriptions of how the process is inhibited.
3. Describe two mechanisms of toxification; compare the mechanisms involved in the detoxification of electrophiles, free radicals and toxicants with no functional groups
4. Compare and contrast first-order and zero order kinetics with regard to the clearance of chemicals from the body
5. Describe five general mechanisms of toxicity and give an example for each.
6. Describe in detail the biotransformation pathway and toxicity mechanism of chronic benzene exposure
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