25 Jul WHAT IS THE PROBABILITY THAT THE FIRST CHILD OF AMANDA AND BRICE WILL HAVE GALACTOSEMIA?
Galactosemia is an autosomal recessive disorder caused by the inability to metabolize galactose a c Show more Galactosemia is an autosomal recessive disorder caused by the inability to metabolize galactose a component of the lactose found in mammalian milk. Galactosemia can be partially managed by eliminating dietary intake of lactose and galactose. Amanda is healthy as are her parents but her brother Alonzo has galactosemia. Brice has a similar family history. He and his parents are healthy but his sister Brianna has galactosemia. Amanda and Brice are planning a family and seek genetic counseling. Based on the information provided complete the following activities and answer the questions. a) Draw a pedigree that includes Amanda Brice their siblings and parents. Identify the genotype of each person using G and g to represent the dominant and recessive alleles respectively. b) What is the probability that Amanda is a carrier of the allele for galactosemia? What is the probability that Brice is a carrier? Explain your reasoning for each answer. c) What is the probability that the first child of Amanda and Brice will have galactosemia? Show your work. d) If the first child has galactosemia what is the probability that two of the next three children will not have galactosemia? Show your work and explain the reasoning for your answer. Show less
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