10 Jun Which of the following is an intermediate in the reaction that forms Ala -tRNA
Question
Which of the following is an intermediate in the reaction that forms Ala -tRNA ?
a) Alanyl -ADP
b) Alanyl- ATP
c) Alanyl- PPi
d) Alanyl -AMP
e) Alanyl -GMP
67. Which of the following is not true of the formation of translation initiation in eukaryotes?
a) elF4F binds to the Y poly(A) tail of the mRNA via poly(A) binding protein (PABP).
b) elF4F binds to the 5′ cap of the mRNA.
c) The pre-initiation complex scans mRNA in a 5′ to 3′ direction until a Shine—Dalgarno sequence is recognized.
d) is escorted to the P site.
e) At least two GTP molecules are hydrolyzed per initiation event.
72. Which of these stages of translation is not a responsibility of the ribosome?
a) monitoring the fidelity of codon-anticodon interactions
b) initiation of translation at an AUG codon
c) monitoring the fidelity of aminoacyl-tRNA charging
d) translocation of the peptidyl-tRNA from the A site to the P site during elongation
e) termination of translation at a STOP codon
73. Which one of the following does not bind the ribosomal A site during bacterial translation?
a) Aminoacyl-tRNA-EF-Tu
b) EF-G
c) RE-I
d) RF-3
e) RRF
74. Which of the following events do not occur in non-stop mRNA decay?
a) A string of lysine residues are added at the C-terminus of the polypeptide.
b) The stalled ribosome recruits Ski 7 protein.
c) Ski 7 protein degrades the defective protein by recognizing the C-terminal poly(Lys) tag.
d) An exosome ribonuclease degrades the mRNA.
e) An mRNA transcript is produced that lacks a stop codon.
79. A single nucleotide insertion mutation holds the potential to alter how many amino acids in the resultant protein:
a) One amino acid
b) Two amino acids
c) Three amino acids
d) More than three amino acids
e) No amino acids, the mutation would be silent
80. Proteins that act by blocking the interaction between activators and RNA polymerase are called:
a) enhancers.
b) coactivators.
c) corepressors.
d) insulators.
e) repressors.
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